Genomics Evidence Neoplasia Information Exchange (GENIE)
The American Association for Cancer Research (AACR)’s Genomics Evidence Neoplasia Information Exchange (GENIE) project aims to aggregate and link clinical-grade cancer genomics data with clinical outcomes for thousands of patients internationally, in hopes to provide statistical power for research. The Princess Margaret Cancer Centre was one of the 7 founding members of the AACR GENIE project, an alliance that has greatly expanded since its inception in 2016, and now includes 18 institutions across the GENIE consortium.
In 2021, CGP submitted genomic and clinical information for 309 cases to GENIE, for a total of 4,878 cases contributed to this effort to date. The registry, after its 11th public data release, now includes 136,096 de-identified genomic records collected from 121,221 patients who were treated at each of the consortium's participating institutions, making it among the largest cancer genomic datasets available to the scientific community for research. Notably in 2021, Dr. Philippe Bedard began his two-year term as the incoming GENIE Chairperson.